what is neprotic syndrome completely explained

#multiple_sclerosis_nephrotic_syndrome
#minimal_change_disease

The most common form of the nephrotic syndrome in children aged 2 to 12 years. It is the cause of nephrotic syndrome in about 90% of children younger than 10 years, about 50% to 70% of older children, and 10% to 15% of adults.

The cause of minimal change disease is not fully known but it is believed to be an immune disorder in which T cells release a cytokine that damages the epithelial foot processes of the glomeruli. This leads to a leakage of albumin by the kidney. Certain events such as a viral infection, an allergic reaction, a bee sting, or an immunization may trigger an attack of MCD.

Symptoms may include edema (swelling) around the eyes, feet and ankles, and abdomen. Laboratory hallmarks of minimal change disease include high urine protein (proteinuria), low blood albumin (hypoalbuminemia) and high cholesterol (hypercholesterolemia). The full constellation of signs and symptoms including edema, large amounts of proteinuria, hypoalbuminemia, and hypercholesterolemia constitute the nephrotic syndrome.

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© Md Sojib Khan